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On March 17, 2025, Mexico adopted a constitutional amendment banning domestic cultivation of “genetically modified” corn

The only genetically engineered (GE) product in commercial production is GE cotton, with obsolete seeds and only in restricted areas. There has been no advance in plant or animal biotechnology development and production, mainly due to policy and regulatory constraints.

In June 2024, the Nicaraguan Institute of Agricultural Protection and Health (IPSA) issued an executive resolution to strengthen the risk mitigation measures for the monitoring and testing of GE grains.

Following the June 2024 election of Claudia Sheinbaum as the next President of Mexico, the sitting President Andres Manuel López Obrador expressed intent to move forward with constitutional reforms in the September 2024 legislative session.

On April 17, 2024, the Government of Mexico published a law in the Official Gazette to establish mandatory warning labeling for products containing genetically engineered ingredients and to enshrine socioeconomic considerations into national food policy.

Mexico's biotechnology regulatory policy environment has become increasingly uncertain under the current administration. The government has not approved any applications for genetically engineered (GE) products for food and feed use since May 2018 and has not approved any permits for planting GE crops since 2019.

There were no significant changes to the Nicaraguan biotechnology regulatory regime in 2023. Nicaraguan biotechnology legislation lacks implementing regulations that would open additional opportunities for farmers and food processors to integrate new technologies into their operations.

On February 13, 2023, Mexico published a modified 2023 Corn Decree in the Diario Official Federal (DOF). The new Presidential decree abrogates the 2020 GE Corn Decree and is immediately effective on February 14, 2023.

Mexico has not officially reported any approvals for genetically engineered (GE) agricultural products for food and feed use since May 2018. Additionally, Mexico has not approved any permit applications for cultivation of GE crop (cotton and alfalfa)...

Despite being passed in 2010, Nicaraguan biotechnology legislation lacks implementing regulations that would open additional opportunities for farmers and food processors to integrate new technologies into their operations. However, Nicaraguan companies continue to regularly import genetically engineered feed grains and oilseed products to support the growing livestock sector.

Mexico has not reported any official biotechnology food or feed products approvals since May 2018. Additionally, Mexico has rejected or delayed all permit applications for cultivation of genetically engineered (GE) cotton in 2019, citing the precautionary principle.

Despite being passed in 2010, Nicaraguan biotechnology legislation lacks implementing regulations that would open opportunities for farmers and food processors to integrate new technologies into their operations. While progress on the regulatory...